Partnering

Flamel Technologies’ drug delivery platforms are widely endorsed by the Industry:

Company Product / Description Indications Technology Status
Coreg CR
(controlled release carvedilol phosphate)
Cardiovascular diseases Micropump Marketed
in the USA
NHP-554
(Micropump aspirin)
Cardiovascular diseases Micropump Approved in EU,
US NDA filing expected in 2012*
IFN-β XL
(interferon beta-1a)
Multiple sclerosis Medusa Phase 1
Undisclosed
THA-902 Pain Medusa Development stage
Controlled release formulations of multiple products, incl. TGF-beta1 inhibitors P144 (Disitertide) and P17, and MTA (methylthioadenosine) Multiple Medusa or Micropump Development stage
 Medusa-based hydrogel depot formulation of the small molecule antibiotic, tigecycline  Multiple Medusa  Development stage
Undisclosed Pain molecules Misuse of
scheduled drugs
Trigger Lock Undisclosed
(see press release April 28,  2011)
In addition, Flamel has several other undisclosed partnerships with leading pharmaceutical and biotechnology companies.

*  New Haven Pharmaceuticals’ website