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Flamel Technologies Announces Results of Annual Meeting

Lyon, France, June 03, 2008 Flamel Technologies (NASDAQ:FLML) today announced the results of its annual meeting held on June 3, 2008. The election of each member of the Board of Directors of the Company for a further one-year term was approved by holders of more than 98% of the Company's shares. Each additional resolution proposed favorably by management at the meeting was approved by holders of more than 93% of the Company's shares.

As a consequence, shareholders re-elected Flamel's Board of Directors. Mr. Elie Vannier, the Senior Advisor and Operating Partner at Oaktree Capital Management, will continue to serve as the Company's non-Executive Chairman. Also re-elected to the Company's Board of Directors were: Mr. Lodewijk J.R. deVink, former Chairman and Chief Executive Officer of Warner Lambert; Dr. Frank Fildes, PhD., former Senior Vice President: Head of Global Drug Development of Astra Zeneca PLC; Mr. Frederic Lemoine, Chairman of the Supervisory Board of AREVA, Mr. John Vogelstein, former President of Warburg Pincus; and Mr. Stephen H. Willard, Flamel's Chief Executive Officer.

"We are pleased to have the strong support of our shareholders," said Mr. Elie Vannier, non-Executive Chairman of Flamel. "As a result of the progress made by our teams under the leadership of Stephen Willard and Rafael Jorda, Flamel has achieved some important successes over the past year which have served to strengthen the Medusa platform. As a result, the Company has signed important agreements with Merck Serono and Wyeth and has another eight Medusa feasibility studies in development with other partners. These relationships, together with the good relationship that the Company enjoys with GlaxoSmithKline for Coreg CR, as well as other Micropump ongoing programs, including TriggerLock®, serve as a strong foundation for the Company's growth going forward."

The Company has 24,066,600 shares issued or outstanding. Votes representing 24,011,961 shares, or 99.8% were tendered.

Flamel Technologies, S.A. is a biopharmaceutical company principally engaged in the development of two unique polymer-based delivery technologies for medical applications. Micropump is a controlled release and taste-masking technology for the oral administration of small molecule drugs. Flamel's Medusa technology is designed to deliver controlled-release formulations of therapeutic proteins.

This document contains "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995, including certain plans, expectations, goals and projections regarding financial results, product developments and technology platforms. All statements that are not clearly historical in nature are forward-looking, and the words "anticipate," "assume," "believe," "expect," "estimate," "plan," will," and similar expressions are generally intended to identify forward-looking statements. All forward-looking statements involve risks, uncertainties and contingencies, many of which are beyond our control, that could cause actual results to differ materially from those contemplated in such forward-looking statements. These risks include risks that products in the development stage may not achieve scientific objectives or milestones or meet stringent regulatory requirements, uncertainties regarding market acceptance of products in development, the impact of competitive products and pricing, and the risks associated with Flamel's reliance on outside parties and key strategic alliances. These and other risks are described more fully in Flamel's Annual Report on the Securities and Exchange Commission Form 20-F for the year ended December 31, 2007. All forward-looking statements included in this release are based on information available at the time of the release. We undertake no obligation to update or alter our forward-looking statements as a result of new information, future events or otherwise.

COREG CR™ is a trademark of GlaxoSmithKline.